In this letter, a numerical technique for solving singular as well as non-singular systems of fractional differential equations with boundary constraint conditions is derived by the cubic B-spline method. These fractional problems are expressed in terms of the conformable fractional operator derivative approach. The method suggested is to check on many cases of both linear and nonlinear systems. Error and convergence analysis of the method via conformable fractional operator are derived and described. Numerical solvability of some test examples is provided in terms of expansions, figures, and tables. The numerical results demonstrate that the approximate solutions converge monotonically and also with fair precision to the exact solutions. In the end, abeyance and future work are given.

Liver disease has become major culprit in expanding mortality rate worldwide mainly due to unavailability of appropriate treatment options. Moreover, cost of treatment is also a very significant hinderance in the treatment of liver disorders. Transplantation of liver is still in infancy state and is associated with staggering cost as well as non-accessibility of donors. Moreover, allopathic medications are double edged sword due to their unfavorable side effects and exaggerated cost of therapy associated with the treatment. So, the focus has been shifted to evaluate the potential of herbal drugs for the management of liver disorders. Although, the course of treatment with the herbals is slow yet, the effects are more promising due to lesser side effects and reduced cost of therapy. Numerous plants have been reported to possess hepatoprotective activity due to presence of phytochemicals like alkaloids, flavanoids, saponins etc. in them. Among these phytoconstituents, saponins are considered more promising candidates in the management of hepatic disorders. The present review is focused on the plants containing saponins used in the management of hepatic disorders with their underlying mechanisms.

Rectal foreign bodies are being increasingly encountered worldwide. Treatment is usually transanal approach but laparotomy can be performed in some cases. We report four patients admitted to the emergency department with insertion of rectal foreign body. Multi disciplinary approach is essential for the diagnosis, management and postextraction evaluation of the patient with a rectal foreign body.

Introduction\nMoral intelligence training by the role-playing model is an important component of nursing student training that can help to improve the individual social growth and professionalism behaviors in students. The present study aimed to determine the comparative effect of moral intelligence training using the lecture and role-playing models on improving the professionalism in nursing students.\nMethod and Materials\nThe present study was a quasi-experimental pre-test post-test single group research. 40 students of the 6th semester of nursing were selected by census method and were included in the study. The demographic, moral intelligence assessment, and professional behavior questionnaires were used to collect data. Questionnaires were completed after teaching moral intelligence through lecturing and role-playing model. Data of questionnaires were analyzed using SPSS V.25 at a 95% confidence level.\nResults\nMean scores of moral intelligence, instructor\'s assessment and professionalism were 65.25± 8.34, 51.62± 6.37 and 37.72 ± 7.33 respectively before the moral intelligence training through role playing, and 82.46±6.54, 67.21± 10.19 and 64.89± 9.51 respectively after training through its. In all three scores, a significant difference was observed between scores of pre- and post-training through the role-playing model.\nConclusion\nThe present study indicated that both methods were effective in improving the moral intelligence and professional behavior in nursing students, but a training method with role playing model was more effective than the lecture model in improving the professional behavior.

The key agreement scheme is an important part of the cryptography theory. The first studies in this field belong to Diffie-Hellman and Merkle. We present a new key agreement scheme using a group\naction of special orthogonal group of 2x2 matrices with real entries on the complex projective line.

Arsenic and accompanying toxic metals can reach honey through water and air, and through the food chain, it can also endanger human health. In addition to other bee products, honey can also be used to monitor the quality of the environment. This paper presents the results of the analysis of a sample of domestic honey for arsenic content from the territory of the town of Bor and its surroundings since Bor is a mining town in eastern Serbia. The copper mine landfills and the locations from which the honey was sampled were presented by a Landsat satellite image, using the USGS archive. Honey samples were analyzed for arsenic ion content in a territory up to 32 km in diameter from the mine, using inductively coupled plasma optical emission spectrometry (ICP-OES). PM10 particles and water were also analyzed for arsenic content at sites near the sampled honey using inductively coupled plasma mass spectrometry (ICP-MS). The obtained results showed that the arsenic content in honey is below the maximum contaminate level (MCL) value and that the honey is not contaminated, despite the fact that the results showed that the concentrations of arsenic in water and PM10 particles are elevated.

This work aims to optimize the parameters influencing the stability of a W/O emulsion and to use it in the extraction of heavy metals present in aqueous media.\nThe study of the emulsion stability shows that a time of emulsification of 10 minutes, a concentration of surfactant, Span80 at 3% (w/w), a concentration of extractant, Triethylamine at 5% (w/w), an internal phase concentration of 0.75 M in H3PO4, a volume ratio of the membrane phase to the internal phase of 1, a volume ratio of the external phase to the emulsion of 20 and a stirring speed of 180 rpm lead to the formulation of a stable emulsion.\nThe results of extraction of the copper ions show that under the best optimized experimental conditions, the extraction yield is equal to 93.33% for 20% extractant content, a contact time of 12 minutes and a concentration of initial copper ions of 400 ppm.\nThe results obtained prove that by an appropriate choice of experimental parameters, it is possible to extract almost all the metal ions present in the solution, which shows that the emulsified liquid membrane extraction (ELM) process is a method of very interesting separation for the removal of heavy metals.