Breast feeding and complementary feeding practices are crucial for health across the life. The purpose of the study was to know some infant feeding practices in a Mexican indigenous population. Twenty Mexican indigenous mothers with children under two-year age answered a semi-structured interview. Most of the mothers reported to feed their children with breast milk during the first months, although exclusive breastfeeding did not meet the recommended time mainly due to cultural factors. We conclude the mothers followed the preferences and signals of the child for complementary feeding, and instinctively determined how and when to offer different foods to breast milk.

This research study is intended to determine the strength behavior of clay based ternary mix concrete composites. Control/Reference concrete mix for the study is made with cement content 400 kg/m3. In order to reduce the use of cement , clay in combination with different additives is used as partial replacement of cement in concrete. Ternary mix composites consisted clay replacements of 24.98%, 21.5% and 17.5% with ternary modifiers (ash, lime and multi- wall carbon nanotube) taking 7.5%, 4.5% and 0.015% parts. In order to evaluate the behavior of different additives in combination with clay as replacement material for cement, the entire research wok is divided in five groups,G1 (Group containing only Cement),G2 (Group containing both Cement-Clay ),G3(Group containing Cement-Clay-Lime ),G4(Group containing Cement-Clay-Ash ) & G5(Group containing Cement-Clay-MWCNT) . All the five groups’ specimens are tested for dry density, water absorption, and workability and Compressive strength. . SEM & EDX analysis is performed for all investigated batches of cement composites. The results of all the evaluated parameters confirmed that clay has good potential to be used as partial replacement material for cement in construction projects. Furthermore it can reduce the cost of the construction project up to 15.4% and C02 production by 10%.

Women have been universally and eternally victimized by stereotyping to the degree that 400 years ago, no less of an expert on females than Cardinal de Richelieu concluded that “Intellect in a woman is unbecoming”.

Natural product and plant based medicine have been gaining importance in the modern medicine due to their therapeutic beneficial effect on Human being for the treatment of different disorders. Now days herbal based product are available in the market and play important role in the Human health due to their protective and defensive mechanism against numerous disorders. In the modern age we can find many herbal based product in the market mainly prepared for prevention and cure of numerous disorders. Benzylisoquinoline alkaloids are the important class of alkaloidal drugs known for their medicinal importance and examples are morphine, codeine, sanguinarine, berberine and canadine. Hydrastis canadensis is the important medicinal plant having alkaloidal class phytochemical such as canadine, hydrastine and “berberine” which have been known for their pharmacological activities. In the present invetiagation, different scientific databases have been searched to collect all the information of canadine. All the data have been categorized into different sections as per the need of the present work. From the analysis of the presented data in the work it was found that Hydrastis Canadensis contain berberine, b-hydrastine, canadine, canadaline, hydrastidine, isohydrastidine, (S)-corypalmine, (S)-isocorypalmine and (S)-tetrahydropalmatine. Pharmacological data analysis revealed the importance of Hydrastis Canadensis for their traditional uses against gastritis, colitis, duodenal ulcers, loss of appetite, liver disease, bile secretions disorder, snake bites and vaginitis. Scientific research data analysis revealed the importance of canadine for their acetylcholinesterase Inhibitory activity, blood disorder, cancer, antimicrobial activity, anti allergic activity, antioxidant activity, muscle atrophy and photo toxicities. Various modern tools have been used for the isolation and analysis of canadine in the Hydrastis Canadensis. Present investigation revealed the medicinal importance and pharmacological activity of canadine in the medicine and other allied sectors. These data will be helpful to the scientist for the development of noble medicine from Hydrastis Canadensis and their important phytochemical canadine.

Objectives: In this case, the story of a woman who lost her eye as a result of neglect by relatives in the first degree was shared. Method: Our case, who was 82 years old female patient, closed her eyes with a bandage she found at home because of the ingrown foreign body in her left eye about two months ago. Afterwards, the patient was brought to the hospital with an ambulance by a relative on the development of pain and suffering in the eye. Results: As a result of ophthalmologic examination, the left eye had conjunctival intense hyperemic purulence along with periorbital edema and helminths were located under the conjunctiva, under the eyelid, under the conjunctiva or deeper into the optic nerve and retina. Discussion: With the increase of elderly population to the total population, elder abuse-neglect increases and continues to be a problem.

Abstract:\nBack ground:\nAs metabolism significantly affects safety and efficacy of drug, determination of the\nmetabolic profile of a drug is a complicated part of drug development. The application of an\nLC–MS based metabolomic approach has gained popularity in identifying drug metabolites,\ndeveloping metabolic maps and lending clues to mechanisms of bioactivation. IC-MS\nworkflows are similar to those of LC-MS and, unlike GC-MS workflows, offer no spectral\nlibraries for compound identification. However, because molecular ions are usually present in\nIC-MS, they can be used as part of the compound identification strategy. By adding\nsuppressor technology, standard IC eluents and methods can be used. Also, the suppressed\nbackground is composed of pure deionized water, allowing easy and advantageous switching\nbetween anion and cation feed into the mass spectrometer.\nMain text: Review is on the significance of Liquid chromatography with tandem Mass\nspectroscopy [LC-MS] of metabolomics at identification and quantification of small\nmolecules involved in metabolic reaction. LC-MS based metabolomic techniques mentioned\nin this review are useful tools for xenobiotic metabolism research since multivariate data\nanalysis in metabolomics. It intends to help investigators understand the challenges in\nmetabolomic studies to determine appropriate experimental, analytical and computational\nmethods to address these challenges. Challenges and current solutions in each step of the\nworkflow are reviewed. LC can be easily integrated with mass spectrometry because analytes\nare often provided in the ionic form needed for MS detection. To begin with, ions can be used\nto search a database of metabolites such as the METLIN database. With recent advances in\nHRAM MS systems, it is now possible to calculate the empirical formula of a target\ncompound from the molecular ion. To better elucidate unknown metabolites, the molecular\nion can be fragmented by MS/MS, and MS/MS spectral libraries can be compared and\nmatched.\nConclusion:\nTherefore, the LC–MS based metabolomic approach is a powerful technique for profiling of\ndrug metabolism and bioactivation.

The research is focused on the topographic modelling and mapping of the Aleutian Trench. The study area is situated in the Bering Sea, a marginal sea located northernmost of the Pacific Ocean, between the Alaska and Kamchatka Peninsula. The geologic setting of the region is notable by the tectonic plate subduction where oceanic Pacific Plate subducts under the North American Plate. Other features include high seismic activity along the Aleutian island arcs bordering the oceanic seafloor. The methodology is based on the GMT which demonstrated excellent possibilities for mapping. Data include ETOPO1 raster grid with 1 arc-minute resolution, EGM96 gravity and vector contour layers of GMT. The research included complex thematic mapping of the region including topographic, contour, geodetic and geophysical mapping, 3D modelling and geomorphological plotting of the 30 cross-section segments of the trench located south-east off the Bowers Ridge. According to the processed ETOPO1 dataset, the minimal depth is at -8480 m, mean is -3089.154 m. The geoid undulations model shows the majority of gravity values lies in the interval between -10 to 20 m with the lowest values along the trench. The statistical histogram shows that the most often depth value in the segment of the Aleutian Trench is -4800 with frequency of 1722 m. Four approaches for the profile linear trend modelling were tested. A surface modelling was performed using xyz modelling from the ASCII data enlarging fragment towards the south-east of the Bowers Ridge. Tested functionality of modules of GMT presented an effective cartographic scripting toolset enabling precise topographic mapping and 3D modelling. The paper contributes to the studies of the Pacific Ocean seafloor bathymetry in context of the geological setting with a case study of the selected segment of the Aleutian Trench near Bowers Ridge area.

Title: “Evaluation of safe blood transfusion practice by assessing haemovigilance among healthcare professionals: An Institutional study”\nIntroduction : Haemovigilance program of India (HvPI) was initiated in the year 2012 and is continuous process of data collection and analysis of transfusion – relates adverse reactions in order to investigate their causes and outcomes to prevent recurrence. The present study was done to ascertain the knowledge, attitude and practice (KAP) of haemovigilance among doctors and health care providers (HCP). The information thus collected would facilitate corrective and preventive actions to be taken to minimie the potential risk associated with blood collection processing and transfusion to patients.\nAims and Objectives:\na) To assess the knowledge, attitude and practice (KAP) of HCP regarding haemovigilance. \nb) To identify the factors which either encourage or discourage transfusion reaction reporting.\nc) Generate evidence based recommendation and create awareness amongst the HCP.\n Methods: It is a cross sectional, prevalidated questionnaire based study carried out among 405 doctors and health care providers in our hospital after obtaining their consent.\nResults: The response rate of the results was 98%. 70% of the responders had poor knowledge whereas, 10% of the responders had good knowledge about HvPI. The awareness of reporting of the transfusion reactions was unsatisfactory with only 21% of the responders having the adequate and relevant information.\nConclusions: In order to improve HvPI, it is essential to improve KAP of the HCP. This study will not directly benefit the participants, but their knowledge and practice will safeguard the wellbeing and healthcare of society. The understanding of KAP regarding HvPI among the HCP is the highest standing determinant of their active participation in HvPI implementation. Hence the present study has been done using the KAP model as a survey tool.

Aerated concrete, which is manufactured from binding material, sand, foaming agent and water, is currently being utilized in the construction industry because of its lightweight and durability. The binding material, cement, along with other materials used in the concrete produces huge carbon footprints during its fabrication. The utilization of natural aggregates name as coarse aggregates depletes the natural resources of the country. Therefore, huge amounts of agricultural wastes have led scholars to investigate the effectiveness of replacing conventional materials used in concrete with agricultural wastes. In the current study, rice husk ash (RHA) was used as supplementary cementing material, thereby reducing the amount of cement used in aerated concrete (AC) mixture will reduce carbon footprints. The experimental and numerical analysis were conducted to investigate structural behaviour of reinforced RAC- B beams subjected to flexural load. Parametric study on structural performance of RAC- B beam under flexure were conducted using finite element analysis (FEA). From the experiment and FEA. Results from the parametric study showed that RAC- 10%RHA-B with higher depth structurally performed better compared to RAC-B under flexure with greater load carrying capacity, lesser maximum deflection, and less cracks developing in the tension area.